AMP-activated protein kinase phosphorylation of endothelial NO synthase
نویسندگان
چکیده
منابع مشابه
AMP-activated protein kinase is involved in endothelial NO synthase activation in response to shear stress.
OBJECTIVE The regulation of AMP-activated protein kinase (AMPK) is implicated in vascular biology because AMPK can phosphorylate endothelial NO synthase (eNOS). In this study, we investigate the regulation of the AMPK-eNOS pathway in vascular endothelial cells (ECs) by shear stress and the activation of aortic AMPK in a mouse model with a high level of voluntary running (High-Runner). METHODS...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1999
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(98)01705-0